Description
Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation.
Applications include:
Promotion of cell attachment and spreading
Cell differentiation and neurite outgrowth
Increased proliferation of PC12 cells
Studies of effects of collagen IV on cell behavior
Cell adhesion assays
Source
Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor
Quality Control
Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
Tested and found negative for bacteria and fungi
Collagen IV purity >90% by SDS-PAGE
Storage
2°C to 8°C. Do not freeze.
Ordering Information:
354416, 354453
Packaging:
Case / 10
Case / 20
Brochure:
Click Here for Brochure
Applications include:
Promotion of cell attachment and spreading
Cell differentiation and neurite outgrowth
Increased proliferation of PC12 cells
Studies of effects of collagen IV on cell behavior
Cell adhesion assays
Source
Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor
Quality Control
Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
Tested and found negative for bacteria and fungi
Collagen IV purity >90% by SDS-PAGE
Storage
2°C to 8°C. Do not freeze.
Ordering Information:
354416, 354453
Packaging:
Case / 10
Case / 20
Brochure:
Click Here for Brochure
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